Her debut novel, Mary Barton (1848), exposed the harsh realities of factory workers' lives and quickly attracted critical attention. This was followed by Cranford (1851–1853), a gentle, humorous portrait of small-town female society, and North and South (1854–1855), which explores class conflict and industrialization through the relationship between a southern gentlewoman and a northern mill owner. Her controversial novel Ruth (1853) sympathetically depicted an unmarried mother, challenging Victorian moral conventions.
Gaskell also wrote The Life of Charlotte Brontë (1857), a pioneering work of literary biography. Her later fiction includes Sylvia's Lovers (1863) and the unfinished Wives and Daughters (1865), widely regarded as her masterpiece. She additionally crafted memorable Gothic ghost stories, and many of her works appeared in Charles Dickens's periodicals. Today, Gaskell is celebrated for her keen social observation, rich characterization, and compassionate storytelling.