Harvey's enduring fame rests on his masterpiece, Exercitatio Anatomica de Motu Cordis et Sanguinis in Animalibus (1628), commonly known as De Motu Cordis. In this landmark work, he demonstrated that blood circulates continuously through the body, driven by the heart—a discovery that overturned centuries of Galenic tradition and laid the foundation of modern physiology.
His second major work, Exercitationes de Generatione Animalium (1651), explored embryology and introduced the influential principle "ex ovo omnia" (all life comes from the egg).
Harvey's books, written with clarity and rigorous empirical method, exemplify the seventeenth-century scientific revolution. Though primarily celebrated as a physician, his writings remain classics of scientific literature, securing his reputation as one of history's most influential authors in medical science. He died in London in 1657, leaving a legacy that transformed both medicine and scientific writing.