During the Civil War, she served as a nurse in Washington, D.C., an experience recorded in her popular book Hospital Sketches (1863). She also published Gothic thrillers under the pseudonym A.M. Barnard. In 1868, at her publisher's request, she wrote Little Women, a semi-autobiographical novel based on her childhood with her three sisters. The book achieved immediate and lasting success, becoming one of the most beloved works in American literature.
Alcott continued the story in sequels including Little Men (1871) and Jo's Boys (1886). Other notable works include An Old-Fashioned Girl (1870) and Eight Cousins (1875). A lifelong advocate for women's rights and abolition, she never married and died in Boston in 1888.