Sinclair's most famous work, The Jungle (1906), revealed the appalling conditions in Chicago's meatpacking industry. Though intended to promote socialism and workers' rights, the novel instead shocked readers with its depiction of unsanitary food production, contributing directly to the passage of the Pure Food and Drug Act and the Meat Inspection Act of 1906. Sinclair famously remarked that he had "aimed at the public's heart and by accident hit it in the stomach."
His other significant works include Oil! (1927), a critique of the petroleum industry that later inspired the film There Will Be Blood; The Brass Check (1919), an attack on the biases of American journalism; and Boston (1928), defending the executed radicals Sacco and Vanzetti. His eleven-novel Lanny Budd series won the Pulitzer Prize in 1943 for Dragon's Teeth.
A dedicated socialist, Sinclair ran for governor of California in 1934. His powerful journalism and reformist spirit left a lasting imprint on American literature and progressive politics.