His breakthrough came with Deluge (1928), a dramatic account of a worldwide flood that annihilates modern civilization. It became an international bestseller, spawned the sequel Dawn (1929), and was adapted into a 1933 Hollywood film whose special-effects techniques helped inspire King Kong. Other significant science fiction includes The Amphibians (1925), The World Below (1929), and The Island of Captain Sparrow (1928).
Wright also made a substantial mark on crime fiction with a popular series of detective novels featuring Merton Home, among them Murder of Darius Pym (1929) and The Hanging of Albert Collins (1930). Beyond writing, he founded a literary agency, edited periodicals, and was an outspoken early advocate of animal rights.
Stylistically influenced by H. G. Wells, Wright remains a notable figure of interwar popular fiction, admired for his imaginative range and doom-laden visions of civilization's collapse.